Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | IL21R | contributors: mct - updated : 24-03-2016 |
HGNC name | interleukin 21 receptor |
HGNC id | 6006 |
|
Location | 16p12.1 Physical location : 27.413.482 - 27.463.362 |
Synonym symbol(s) | NILR, MGC10967, IL-21R |
DNA |
TYPE | functioning gene |
STRUCTURE | 48.39 kb 9 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| lymphoma | fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
conjugated | GlycoP |
mono polymer | heteromer , dimer |
HOMOLOGY |
Homologene |
FAMILY | |
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CATEGORY | receptor membrane |
SUBCELLULAR LOCALIZATION | plasma membrane |
text | type I membrane protein |
basic FUNCTION | |
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CELLULAR PROCESS | cell life, differentiation |
cell life, proliferation/growth | |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | signal transduction |
IL21/IL21R pathway is a critical component of the memory B cell response |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
| |
|
cell & other |
REGULATION |
Other | CASP8 cleavage of IL21R is a negative feedback regulator of IL21 signaling |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |