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FLASH GENE
Symbol GOT2 contributors: - updated : 04-01-2006
HGNC name glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
HGNC id 4433
Location 16q21      Physical location : 58.741.034 - 58.768.246
Synonym name aspartate aminotransferase 2
Synonym symbol(s) MDAT1, FLJ40994
EC.number 2.6.1.1
DNA
TYPE functioning gene
STRUCTURE 27.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked Y status confirmed
Physical map
MGC10992 16q13 hypothetical protein LOC92922 GPR114 16q13 G protein-coupled receptor 114 LOC255519 16q13 similar to high mobility group protein homolog HMG4 GPR56 16q13 G protein-coupled receptor 56 GPR97 16q13 G protein-coupled receptor 97 DKFZp434I099 16q13 hypothetical protein DKFZp434I099 KATNB1 16q13 katanin p80 (WD repeat containing) subunit B 1 KIFC3 16q13-q21 kinesin family member C3 LOC388282 16 hypothetical gene supported by AF452719; BC041062 CNGB1 16q13 cyclic nucleotide gated channel beta 1 TEPP 16q13 testis/prostate/placenta-expressed protein ZNF319 16q21 zinc finger protein 319 FLJ13154 16q13 hypothetical protein FLJ13154 MMP15 16q13-q21 matrix metalloproteinase 15 (membrane-inserted) GTL3 16q13 likely ortholog of mouse gene trap locus 3 CSNK2A2 16p13.3-p13.2 casein kinase 2, alpha prime polypeptide HSPC065 16q13 HSPC065 protein FLJ13912 16q13 hypothetical protein FLJ13912 NDRG4 16q21-q22.3 NDRG family member 4 FLJ21148 16q13 hypothetical protein FLJ21148 KIAA1007 16q21 hypothetical protein FLJ21148 FLJ10815 16q13 hypothetical protein FLJ10815 GOT2 16q21 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestivemouthtongue  highly
Lymphoid/Immunespleen   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
basic FUNCTION
  • plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS