Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GNAO1 | contributors: mct - updated : 15-10-2015 |
HGNC name | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
HGNC id | 4389 |
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Corresponding disease |
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Location | 16q12.2 Physical location : 56.225.250 - 56.391.355 | ||
Synonym symbol(s) | G-ALPHA-o, GNAO |
DNA |
TYPE | functioning gene |
STRUCTURE | 166.11 kb 9 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | LipoP |
HOMOLOGY |
Homologene |
FAMILY | G alpha family, subfamily 1 |
CATEGORY | signaling , receptor |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,Golgi | |
intracellular,nucleus |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
GNAO1-GPRIN1 pathway could mediate significant roles in neuronal migration and differentiation at embryonic stages and exert functions in wiring and/or maintenance of specific neural circuitries at postnatal to adult stages |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | EEIV |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |