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FLASH GENE
Symbol GIN1 contributors: mct - updated : 20-01-2009
HGNC name gypsy retrotransposon integrase 1
HGNC id 25959
Location 5q21.1      Physical location : 102.421.703 - 102.455.842
Synonym name
  • zinc finger, H2C2 domain containing
  • Ty3/Gypsy integrase 1
  • gypsy integrase 1
    • Synonym symbol(s) ZH2C2, FLJ20125, GIN-1, TGIN1
    DNA
    TYPE functioning gene
    STRUCTURE 34.14 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    Map cen - D5S2683 - D5S1604E - GIN1 - D5S456 - D5S409 - qter
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 3549 59.71 522 - 2001 11470852
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon   Homo sapiens
     stomach     Homo sapiens
    Endocrineparathyroid   highly Homo sapiens
    Nervousbrain     Homo sapiens
    Urinarykidney     Homo sapiens
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumcardiac   Homo sapiens
    Nervouscentral   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • characteristic H2C2, DDE, and GPY/F motifs found in many retroviral and retrotransposon integrases
    • HOMOLOGY
    interspecies ortholog to murine Gin1 (85 p100)
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may be part of an analogous defense system, perhaps having contributed to the virtual absence of Ty3/Gypsy elements in mammalian genomes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS