Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | G6PC | contributors: mct/npt/pgu - updated : 03-06-2020 |
HGNC name | glucose-6-phosphatase, catalytic subunit |
HGNC id | 4056 |
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Corresponding disease |
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Location | 17q21.31 Physical location : 41.052.814 - 41.065.386 | ||
Synonym name | glucose-6-phosphatase alpha | ||
Synonym symbol(s) | G6PT, G6PC1, G-6-Pase, MGC163350, GSD1, GSD1a, G6Pase | ||
EC.number | 3.1.3.9 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | head to head |
STRUCTURE | 13.64 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
intracellular,cytoplasm,cytosolic,microsome |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | GSD1A |
Susceptibility | sudden and unexpected death |
Variant & Polymorphism other | promoter polymorphism, which lowers expression, potentially increasing risk of hypoglycaemia and hence risk of sudden and unexpected death |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |