basic FUNCTION
| acting as an orphan receptor involved in G-protein coupled receptor protein signaling pathway |
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having purinergic nucleotide receptor activity |
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inducing apoptosis via TP53/Bax pathway in an ischemia/reperfusion paradigm |
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acting as a receptor for short chain fatty acids through a G(i)- protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium |
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acting as a rhodopsin-like receptor |
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mediate short-chain fatty acids signaling in mammary epithelial cells and thereby play an important role in their stress management |
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potential regulator of host energy balance through effects that are dependent upon the gut microbiota |
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its expression in colonic mucosa may function as a sensor for luminal short-chain fatty acids |
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G protein-coupled receptor activated by short chain carboxylic acids |
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might play an important role in sympathetic ganglia |
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associated with histone acetylation and might be involved in the acetylation-related regulation of cell processes including proliferation, apoptosis, and the cell cycle |
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its expression is mediated via an internal ribosome entry site located in the intergenic region of a bicistronic mRNA |
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beta cell-specific expression of the FFAR3 gene is controlled by an unusual mechanism that involves control at both the level of transcription and translation |
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play important roles not only as essential nutritional components but also as signaling molecules in numerous physiological processes |
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is involved in SCFA-dependent energy regulation, and in host energy regulation |