Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | FANCF | contributors: mct/npt - updated : 08-06-2021 |
HGNC name | Fanconi anemia, complementation group F |
HGNC id | 3587 |
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Corresponding disease |
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Location | 11p14.3 Physical location : 22.644.078 - 22.647.387 | ||
Synonym name | protein FACF | ||
Synonym symbol(s) | FAF, MGC126856 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | |
text | intron less |
STRUCTURE | 3.31 kb 1 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Promoter |
Binding site | |
text structure | FANCF promoter cis element, which is activated by IRF8 in differentiating myeloid cells (Saberwal 2009) |
MAPPING | cloned | Y | linked | N | status | provisional |
Map | pter - D11S1359 - FANCF FANCF - D11S329 - cen |
Authors | de Winter (00) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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mono polymer | complex |
HOMOLOGY |
intraspecies | homolog to prokaryotic RNA-binding protein ROM |
Homologene |
FAMILY |
CATEGORY | regulatory , DNA associated |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus,nucleoplasm |
CELLULAR PROCESS | nucleotide, genomic integrity |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
chromosome instability pathway |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | FANCF |
related resource | Fanconi Anaemia Mutation Database |
Other morbid association(s) |
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Susceptibility |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |