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FLASH GENE
Symbol EVX2 contributors: npt/ - updated : 20-10-2007
HGNC name even-skipped homeobox 2
HGNC id 3507
Corresponding disease
DEL2Q31 chromosome 2q interstitial deletion, including 2q31.1
PSDY2 polysyndactyly 2
Location 2q31.1      Physical location : 176.944.836 - 176.948.690
Synonym name
  • eve, even-skipped homeo box homolog 2 (Drosophila)
  • Drosophila even-skipped pair rule gene homolog 2 (murine Evx2)
    • DNA
    TYPE functioning gene
    STRUCTURE 3.86 kb     3 Exon(s)
    MAPPING cloned Y linked N status confirmed
    Map see HOXD@
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 1617 47.6 476 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • helix-turn-helix, DNA binding domain
    • HOMOLOGY
    interspecies homolog to Drosophila even-skipped pair rule gene 2
    homolog to murine Evx2
    Homologene
    FAMILY
  • even-skipped homeobox family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PSDY2 , DEL2Q31
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS