basic FUNCTION
| provide positional cues required for the normal morphogenesis of skeletal elements (![](pubmed.jpg) |
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acts both as a ligand and as a receptor in a tissue-specific manner during embryogenesis (![](pubmed.jpg) |
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ligand for eph-related receptor tyrosine kinase, involved in short-range contact-mediated axonal guidance |
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may be playing a role in cell adhesion and function in the development or maintenance of the nervous system |
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playing a role in tissue boundary formation |
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binds to the cytoplasmic domain of EFNB1, which is expressed in cortical neural progenitors and plays a role in neural progenitor cell maintenance ![](pubmed.jpg) |
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essential components of the Reelin receptor/signalling pathway to control neuronal migration during the development of the nervous system (![](pubmed.jpg) |
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novel function of EFNB1 and EFNB2 in stabilizing IL7R expression at the post-translational level ![](pubmed.jpg) |
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function of EFNB1 in the T cell compartment could be compensated by other members of the EFN family, and that such redundancy safeguards the pivotal roles of EFNB1 in T cell development and function ![](pubmed.jpg) |
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is necessary for cardiac tissue architecture cohesion by stabilizing the adult cardiomyocytes (CM) morphology through regulation of its lateral membrane ![](pubmed.jpg) |
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EFNB1 inhibits nonradial migration of pyramidal neurons, thereby controlling the pattern of cortical columns ![](pubmed.jpg) |
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contributes to the suppression of adipose inflammatory response ![](pubmed.jpg) |
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is a novel microtubule associated protein (MAP) ![](pubmed.jpg) |
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importance of ephrinB1 signalling between cells of the skeleton required for endochondral ossification ![](pubmed.jpg) |
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EFNB1-mediated repulsion and signaling control germinal center T cell territoriality and function ![](pubmed.jpg) |
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influences bone loss during the development of osteoporosis, by regulating both osteoblast and osteoclast formation and function, leading to a loss of skeletal integrity ![](pubmed.jpg) |
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contributes to the stromal support of hematopoietic stem/progenitor cells (HSPCs) function and maintenance and may be an important factor in regulating the HSPC niche ![](pubmed.jpg) |