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FLASH GENE
Symbol DPH2 contributors: npt/ - updated : 07-03-2006
HGNC name DPH2 homolog (S. cerevisiae)
HGNC id 3004
Location 1p34.1      Physical location : 44.435.652 - 44.439.044
Synonym name
  • diptheria toxin resistance protein required for diphthamide biosynthesis-like 2 (S. cerevisiae)
  • DPH2-like 2 (S. cerevisiae)
  • diphthamide biosynthesis protein 2 homolog-like 2
    • Synonym symbol(s) DPH2L2
    DNA
    TYPE functioning gene
    STRUCTURE 3.39 kb     6 Exon(s)
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 2513 51 489 - Schultz (1998)
    5 - 1829 - 261 - Schultz (1998)
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to yeast S.cerevisiae diphthamide biosynthesis protein 2-like 2
    ortholog to murine Sph2l2
    Homologene
    FAMILY
  • DPH1/DPH2 family
  • diphthamide synthesis DPH2 subfamily
    • CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • required for diphteria toxin resistance
  • acting in diphthamide biosynthesis (Webb 2008)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS