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FLASH GENE
Symbol DPH2 contributors: npt/ - updated : 07-03-2006
HGNC name DPH2 homolog (S. cerevisiae)
HGNC id 3004
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 2513 51 489 - Schultz (1998)
5 - 1829 - 261 - Schultz (1998)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to yeast S.cerevisiae diphthamide biosynthesis protein 2-like 2
ortholog to murine Sph2l2
Homologene
FAMILY
  • DPH1/DPH2 family
  • diphthamide synthesis DPH2 subfamily
  • CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • required for diphteria toxin resistance
  • acting in diphthamide biosynthesis (Webb 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS