Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CYP2C19 | contributors: mct - updated : 18-04-2019 |
HGNC name | cytochrome P450, family 2, subfamily C, polypeptide 19 |
HGNC id | 2621 |
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Corresponding disease |
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Location | 10q23.33 Physical location : 96.522.462 - 96.612.670 | ||
Genatlas name | xenobiotic monooxygenase | ||
Synonym name | |||
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Synonym symbol(s) | CPC1, CYP2C, P450C2C, CPCJ | ||
EC.number | 1.14.14.51 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
STRUCTURE | 92.87 kb 9 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | N | linked | N | status | confirmed |
Map | cen - CYP2C18 - CYP2C19 - CYP2C9 - CYP2C8 - qter |
Authors | Gray (95), Finta (00) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | HemoP |
mono polymer | monomer |
HOMOLOGY |
interspecies | homolog to C.Elegans C12D6.7 |
Homologene |
FAMILY | |
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CATEGORY | enzyme , transport |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
intracellular,cytoplasm,cytosolic,microsome |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | electron transport , detoxification |
PATHWAY |
metabolism | drug |
signaling |
oxidative metabolism |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, nucleotide, |
NADPH, heme |
protein | |
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cell & other |
REGULATION |
induced by | drugs,pesticides carcinogens |
ASSOCIATED DISORDERS |
corresponding disease(s) | CYP2C19DM |
related resource | Human Cytochrome P450 (CYP) Allele Nomenclature Committee |
Susceptibility |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |