basic FUNCTION
| involved in hydroxylation of mephenytoin and other xenobiotics (omeprazole) |
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cytochrome P450 monooxygenase that contributes significantly to metabolic clearance of several widely prescribed drugs |
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CYP2C9 and CYP2C19 are important drug-metabolizing enzymes and together metabolize approximately 20 p100 of therapeutically used drugs |
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CYP2C19 genotypes had significant impact on clopidogrel response and prognosis of patients with stroke |
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plays a role in the biotransformation of clinically relevant drugs as well as endogenous compounds, including sex hormones, which are known to be modulators of food intake and energy balance |
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is an important member of the cytochrome P450 (CYP450) enzyme super family and is responsible for clearing approximately 10p 100 of commonly used clinical drugs that undergo phase I metabolism |