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FLASH GENE
Symbol CLIC6 contributors: mct/npt - updated : 21-05-2008
HGNC name chloride intracellular channel 6
HGNC id 2065
Location 21q22.12      Physical location : 36.041.687 - 36.090.519
Synonym name
  • parchorin
  • chloride intracellular channel 5
    • Synonym symbol(s) CLIC5, CLIC1L, CLICL1
    DNA
    TYPE functioning gene
    STRUCTURE 48.00 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence cytosine-phosphate-guanine/HTF
    motif
    text structure a GC rich segment, which encodes a 10 amino acid motif repeated 14 times in the amino-terminus
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 3800 - 686 - Friedli (2003)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivestomach    
    Reproductivefemale systemuterus   
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • glutathione S-transferase domain
  • a GC rich segment, which encodes a 10 amino acid motif repeated 14 times in the amino-terminus
    • HOMOLOGY
    Homologene
    FAMILY
  • chloride intracellular channel family
    • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • may play a critical role in water-secreting cells,
    • possibly through the regulation of chloride ion transport
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with the DRD2, DRD3, and DRD4 and MPDZ
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS