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FLASH GENE
Symbol CLIC6 contributors: mct/npt - updated : 21-05-2008
HGNC name chloride intracellular channel 6
HGNC id 2065
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach    
Reproductivefemale systemuterus   
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • glutathione S-transferase domain
  • a GC rich segment, which encodes a 10 amino acid motif repeated 14 times in the amino-terminus
  • HOMOLOGY
    Homologene
    FAMILY
  • chloride intracellular channel family
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • may play a critical role in water-secreting cells,
  • possibly through the regulation of chloride ion transport
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with the DRD2, DRD3, and DRD4 and MPDZ
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS