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FLASH GENE
Symbol CD37 contributors: - updated : 28-12-2006
HGNC name CD37 antigen
HGNC id 1666
Location 19q13.3      Physical location : 49.838.676 - 49.843.859
Genatlas name cell differentiation antigen 37 (gp52-40), 52-40kDa, membrane glycoprotein, identified by monoclonal antibodies G28-1, Y29/55, RFB-7, MB-1, M-B371, M-B372
Synonym name
  • leukocyte surface antigen CD37
  • cell differentiation antigen 37
  • Synonym symbol(s) GP52-40, MGC120234, TSPAN26
    DNA
    TYPE functioning gene
    STRUCTURE 5.00 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Physical map
    NTF5 19q13.3 neurotrophin 5 (neurotrophin 4/5) KCNA7 19q13.4 potassium voltage-gated channel, shaker-related subfamily, member 7 SNRP70 19q13.3 small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen) LIN7B 19q13.3 lin-7 homolog B (C. elegans) FLJ10490 19q13.33 hypothetical protein FLJ10490 PPFIA3 19q13.3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 HRC 19q13.3 histidine rich calcium binding protein TRPM4 19q13.32 transient receptor potential cation channel, subfamily M, member 4 NTT5 19q13.1-q13.4 transient receptor potential cation channel, subfamily M, member 4 CD37 19q13.3 CD37 antigen DKKL1-pending 19q13.33 soggy-1 gene TEAD2 19q13.3 TEA domain family member 2 FLJ32658 19q13.33 hypothetical protein FLJ32658 TIP39 19q13.33 tuberoinfundibular 39 residue protein precursor LOC390955 19 similar to ENSANGP00000004655 SLC17A7 19q13 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 FLJ20643 19q13.33 hypothetical protein FLJ20643 MGC10204 19q13.33 hypothetical protein MGC10204 FLT3LG 19q13.3 fms-related tyrosine kinase 3 ligand RPL13A 19q13.4 ribosomal protein L13a RPS11 19q13.3 ribosomal protein S11 FCGRT 19q13.3 Fc fragment of IgG, receptor, transporter, alpha RCN3 19q13.33 reticulocalbin 3, EF-hand calcium binding domain
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1263 - 281 - Suzuki
    - - 1229 - 213 - Suzuki
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node   highly
     spleen   highly
     tonsils   highly
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticleukocyte
    Lymphoid/Immunelymphocyte
    cell lineage
    cell lines
    fluid/secretion lymph
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY tetraspanin (TM4SF) family
    CATEGORY antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • mediating signal transduction events that play a role in the regulation of cell development, activation, growth and motility
  • cell surface glycoprotein complexing with integrins and other transmembrane 4 superfamily proteins and playing a role in T-cell-B-cell interactions
  • playing a regulatory role in T cell proliferation by influencing early events of TCR signaling
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS