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FLASH GENE
Symbol CD37 contributors: - updated : 28-12-2006
HGNC name CD37 antigen
HGNC id 1666
DNA
TYPE functioning gene
STRUCTURE 5.00 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
NTF5 19q13.3 neurotrophin 5 (neurotrophin 4/5) KCNA7 19q13.4 potassium voltage-gated channel, shaker-related subfamily, member 7 SNRP70 19q13.3 small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen) LIN7B 19q13.3 lin-7 homolog B (C. elegans) FLJ10490 19q13.33 hypothetical protein FLJ10490 PPFIA3 19q13.3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 HRC 19q13.3 histidine rich calcium binding protein TRPM4 19q13.32 transient receptor potential cation channel, subfamily M, member 4 NTT5 19q13.1-q13.4 transient receptor potential cation channel, subfamily M, member 4 CD37 19q13.3 CD37 antigen DKKL1-pending 19q13.33 soggy-1 gene TEAD2 19q13.3 TEA domain family member 2 FLJ32658 19q13.33 hypothetical protein FLJ32658 TIP39 19q13.33 tuberoinfundibular 39 residue protein precursor LOC390955 19 similar to ENSANGP00000004655 SLC17A7 19q13 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 FLJ20643 19q13.33 hypothetical protein FLJ20643 MGC10204 19q13.33 hypothetical protein MGC10204 FLT3LG 19q13.3 fms-related tyrosine kinase 3 ligand RPL13A 19q13.4 ribosomal protein L13a RPS11 19q13.3 ribosomal protein S11 FCGRT 19q13.3 Fc fragment of IgG, receptor, transporter, alpha RCN3 19q13.33 reticulocalbin 3, EF-hand calcium binding domain
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1263 - 281 - Suzuki
- - 1229 - 213 - Suzuki
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node   highly
 spleen   highly
 tonsils   highly
Reproductivemale systemprostate   
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow  highly
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
Lymphoid/Immunelymphocyte
cell lineage
cell lines
fluid/secretion lymph
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY tetraspanin (TM4SF) family
CATEGORY antigen
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • mediating signal transduction events that play a role in the regulation of cell development, activation, growth and motility
  • cell surface glycoprotein complexing with integrins and other transmembrane 4 superfamily proteins and playing a role in T-cell-B-cell interactions
  • playing a regulatory role in T cell proliferation by influencing early events of TCR signaling
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS