Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CCRL2 | contributors: mct - updated : 21-10-2013 |
HGNC name | chemokine (C-C motif) receptor-like 2 |
HGNC id | 1612 |
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Location | 3p21.31 Physical location : 46.448.720 - 46.451.013 |
Synonym name | |
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Synonym symbol(s) | HCR, CKRX, CRAM-A, CRAM-B, CCR6, CCR11, MGC116710 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
STRUCTURE | 2.29 kb 2 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
Map | pter - D3S3582 - CCRL2 - D3S3560 - D3S1581 - D3S3648 - D3S1578 - D3S1588 - cen |
Authors | GeneMap (98) |
regionally located | located in a region where the chemokine receptor gene are clustered |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
tissue |
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cells |
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cell lineage | primary neutrophils, primary monocytes |
cell lines | |
fluid/secretion |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES |
STRUCTURE |
motifs/domains
| seven transmembrane segments (7TM) receptor |
HOMOLOGY |
intraspecies | homolog to CCR1 |
Homologene |
FAMILY | G protein coupled receptor family |
CATEGORY | receptor membrane G |
SUBCELLULAR LOCALIZATION | plasma membrane |
basic FUNCTION | |
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CELLULAR PROCESS | cell communication |
cell migration & motility |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
Other | upregulated on neutrophil activation and during monocyte to macrophage differentiation |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility | to rheumatoid arthritis |
Variant & Polymorphism | |
Candidate gene |
Marker |
Therapy target |
ANIMAL & CELL MODELS |