basic FUNCTION
| regulator of progression through G1 phase during the cell cycle 3 |
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involved in the loss of cell cycle control in a small fraction of malignant glioma |
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having important implications for a role for lamin A/C in muscle differentiation |
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playing a crucial role in adipocyte differentiation by regulating mitotic clonal expansion |
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central coordinator that controls the organization of a complex set of proteins that regulate autophagy, formation of the monocyte-adhesive hyaluronan matrix, and CEBPA-mediated lipogenesis |
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role of CCND3/CDK11A complex in repressing the Schwann cells proliferation and inducing its apoptosis |
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primary driver of the cell cycle, in cooperation with CCND1 that integrates extracellular mitogenic signaling |
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predominantly regulate progression through the cell cycle by their interactions with cyclin-dependent kinases (CDKs) |
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uniquely required for germinal center progression |
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selectively required for proliferative expansion of germinal center B cells |
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primes myoblasts for differentiation by enhancing muscle specific gene expression and cell cycle exit |
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CCND3 and its partner CDK6 were required for the proliferation of Burkitt lymphoma (BL) |
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regulates the number of cell divisions that erythroid precursors undergo during terminal differentiation, thereby controlling erythrocyte size and number |
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likely subnuclear compartmentalization enables CCND3 to drive cell cycle progression and repress V gene accessibility, thereby ensuring coordination of proliferation with immunoglobulin recombination |
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critically required for proper developmental progression of myogenic progenitors |
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plays a cell-autonomous and nonredundant function in regulating the dynamic balance between proliferation, differentiation, and self-renewal that normally establishes an appropriate pool size of adult satellite cells |