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FLASH GENE
Symbol CCND3 contributors: mct - updated : 30-08-2016
HGNC name cyclin D3
HGNC id 1585
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
with CDKN1B in agressive B cell lymphoma, glioblastoma and gliosarcoma
tumoral   translocation    
in multiple myeloma
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerhemopathy 
potential therapeutic target for germinal center-derived B-cell malignancies
ANIMAL & CELL MODELS
Ccnd3(-/-) mice exhibit a B-cell-intrinsic defect in germinal center maturation and fail to generate an affinity-matured IgG response