Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | C7 | contributors: mct - updated : 15-01-2007 |
HGNC name | complement component 7 |
HGNC id | 1346 |
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Corresponding disease |
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Location | 5p13 Physical location : 40.909.598 - 40.983.039 | ||
Synonym name | complement component 7,beta-2 globulin |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | opposite orientation, tail to tail |
text | tail to tail with C6 |
STRUCTURE | 73.00 kb 18 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | GlycoP |
isoforms | Precursor |
HOMOLOGY |
interspecies | ortholog to murine C7 |
Homologene |
FAMILY | complement C6/C7/C8/C9 family |
CATEGORY | immunity/defense , secretory |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,Golgi | |
text | located in the Golgi apparatus (Rameix-Welti 2007) |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | immunity/defense |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | C7D |
related resource | C7base - Mutation registry for C7 deficiency |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |