basic FUNCTION
| may be participating in reverse cholesterol transport from peripheral cells to the liver |
|
having lipid binding activity that, when overproduced intracellularly, induces autophagic cell death  |
|
BH3-only pro-death protein, which may play a role in cytokine-induced inflammatory response  |
|
lipid-binding protein with high affinity for phosphatidic acid and cardiolipin and less affinity for various phosphoinositides  |
|
serum factor that lyses trypanosomes  |
|
APOL1 possesses both extra- and intra-cellular functions crucial in host defense and cellular homeostatic mechanisms  |
|
role of APOL1 in renal cell carcinoma (RCC) and chronic kidney disease, highlighting the critical function of APOL1 in autophagy  |
|
APOL1 gene product is toxic to kidney cells, and its G1 and G2 alleles are strongly associated with increased risk for kidney disease progression in African Americans  |
|
potential pivotal role for mitochondrial dysfunction in APOL1-associated kidney disease  |
|
APOL1 is an innate immune effector that protects human beings from infection by some trypanosomal parasites  |
|
role for APOL1 in the development of preeclampsia  |
|
have important functions in the kidney  |