basic FUNCTION
| may be participating in reverse cholesterol transport from peripheral cells to the liver |
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having lipid binding activity that, when overproduced intracellularly, induces autophagic cell death |
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BH3-only pro-death protein, which may play a role in cytokine-induced inflammatory response |
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lipid-binding protein with high affinity for phosphatidic acid and cardiolipin and less affinity for various phosphoinositides |
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serum factor that lyses trypanosomes |
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APOL1 possesses both extra- and intra-cellular functions crucial in host defense and cellular homeostatic mechanisms |
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role of APOL1 in renal cell carcinoma (RCC) and chronic kidney disease, highlighting the critical function of APOL1 in autophagy |
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APOL1 gene product is toxic to kidney cells, and its G1 and G2 alleles are strongly associated with increased risk for kidney disease progression in African Americans |
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potential pivotal role for mitochondrial dysfunction in APOL1-associated kidney disease |
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APOL1 is an innate immune effector that protects human beings from infection by some trypanosomal parasites |
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role for APOL1 in the development of preeclampsia |
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have important functions in the kidney |