Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ACER3 | contributors: mct - updated : 03-07-2018 |
HGNC name | alkaline ceramidase 3 |
HGNC id | 16066 |
|
Corresponding disease |
| ||
Location | 11q13.5 Physical location : 76.571.916 - 76.734.850 | ||
Synonym name | |||
| |||
| |||
Synonym symbol(s) | APHC, FLJ11238, PHCA, PLDECO | ||
EC.number | 3.5.1.23 |
DNA |
TYPE | functioning gene |
STRUCTURE | 165.92 kb 11 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | pregnancy |
Text | placenta |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
conjugated | GlycoP |
HOMOLOGY |
interspecies | homolog to murine Acer3 (88.4pc) |
homolog to rattus Phca (88.0pc) |
intraspecies | homolog to ACER2, ACER1 |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
intracellular,cytoplasm,organelle,Golgi | |
text | |
|
basic FUNCTION | |
| |
| |
| |
| |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
activated by | Ca2+ |
inhibited by | Zn2+ |
ASSOCIATED DISORDERS |
corresponding disease(s) | PLDECO |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
|
|
|
ANIMAL & CELL MODELS |
Acer3 deficient mice demonstrated impairment in motor coordination and balance capabilities |