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FLASH GENE

Symbol

DLG1

contributors: shn/pgu - updated : 28-08-2015

HGNC name	discs, large homolog 1 (Drosophila)
HGNC id	2900

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Dlgh1(-/-) mice developed severe urinary tract abnormalities, including congenital hydronephrosis
	Dlg1-null mice exhibit hydronephrosis, hydroureter, and occasionally hypoplastic kidneys
	deletion of mice Dlgh-1 caused open eyelids, open neural tube, and misorientation of cochlear hair cell stereociliary bundles, indicative of defects in planar cell polarity (PCP)