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FLASH GENE
Symbol CHD8 contributors: mct/shn - updated : 09-09-2009
HGNC name chromodomain helicase DNA binding protein 8
HGNC id 20153
ANIMAL & CELL MODELS
  • Chd8/ mouse embryos was arrested at gastrulation and died early during embryogenesis, manifesting widespread apoptosis, whereas deletion of p53 ameliorated this developmental arrest
  • Chd8 +/- mice appeared normal and were fertile