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FLASH GENE

Symbol

GRHL2

contributors: mct - updated : 25-08-2015

HGNC name	grainyhead-like 2 (Drosophila)
HGNC id	2799

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	up-regulation of grainyhead-like 2 (Grhl2) in Axial defects mutant embryos, over-expression of Grhl2 causing cranial neural tube defects
	placentas from Grhl2-deficient mouse embryos displayed defects in BCT cell polarity and basement membrane integrity at the chorioallantoic interface, as well as a severe disruption of labyrinth branching morphogenesis