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FLASH GENE

Symbol

GALC

contributors: mct - updated : 04-11-2014

HGNC name	galactosylceramidase (Krabbe disease)
HGNC id	4115

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Twi-5J display gliosis and globoid cell accumulation in the forebrain, and psychosine accumulation without extensive perturbations in CNS myelination
	proliferation/self-renewal of neural stem cells (NSCs) and survival of their neuronal and oligodendroglial progeny are impaired in Galc-deficient mice