Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --over
|  
|
significantly increased podocyte motility, and dramatically increased the expression of nephrin | tumoral
|  
|  
| --over
|  
|
in esophageal cancer tissues | constitutional
|  
|  
|  
| loss of function
|
does not affect the number of APOB-containing lipoproteins secreted by the liver but alters the particles that are made such that they are cleared more rapidly from the circulation via a noncanonical pathway(s) | constitutional
|  
|  
| --over
|  
|
in glomerular podocytes of nephrotic syndrome | constitutional
|  
|  
|  
| loss of function
|
results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG) | |