Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
|  
|  
|
frequently inactivated in human gastric cancer and in several other cancers due to promoter hypermethylation |
tumoral
|  
|  
| --low
|  
|
in samples of acute leukaemia and associated with an inferior overall survival |
tumoral
|  
|  
| --low
|  
|
by promoter hypermethylation in gastric and colorectal cancers |
tumoral
|  
|  
| --low
|  
|
by promoter hypermethylation is a common, tissue-specific event in esophageal adenocarcinoma, occurs early during Barrett's-associated esophageal neoplastic progression, and is a potential biomarker for the early detection of esophageal adenocarcinoma |
tumoral
| imprinting
|  
|  
|  
|
epigenetic silencing of AKAP12 may be involved in myeloid malignancies |
tumoral
|  
|  
| --low
|  
|
in hepatocellular carcinoma tissues through promoter hypermethylation |