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FLASH GENE

Symbol

WASL

contributors: npt/mct/pgu - updated : 19-08-2010

HGNC name	Wiskott-Aldrich syndrome-like
HGNC id	12735

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function deficiency leads to reduced adhesion to fibronectin and increased cell motility tumoral   LOH     in breast cancer constitutional     --low   in men with idiopathic azoospermia

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer lung   is an important potential therapeutic target in lung cancer invasion

ANIMAL & CELL MODELS