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FLASH GENE

Symbol

ZBTB7A

contributors: mct/npt - updated : 20-12-2017

HGNC name	zinc finger and BTB domain containing 7A
HGNC id	18078

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   aberrantly, in breast, lung, colon, prostate and bladder carcinomas tumoral germinal mutation       in acute myeloid leukaemia with t(8;21) translocation tumoral       loss of function loss-of-function mutation in ZBTB7A is a novel mechanism causing elevated glycolysis in human cancer, which carries important therapeutic implication

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	is a potential prognostic biomarker for breast cancer
Therapy target	attractive therapeutic target for the treatment of many types of cancer

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   aberrantly, in breast, lung, colon, prostate and bladder carcinomas tumoral germinal mutation       in acute myeloid leukaemia with t(8;21) translocation tumoral       loss of function loss-of-function mutation in ZBTB7A is a novel mechanism causing elevated glycolysis in human cancer, which carries important therapeutic implication

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	is a potential prognostic biomarker for breast cancer
Therapy target	attractive therapeutic target for the treatment of many types of cancer

ANIMAL & CELL MODELS