Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

KCNN4

contributors: mct - updated : 25-08-2015

HGNC name	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
HGNC id	6293

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

DHS2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in pancreas and ovarian tumors

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed allergy asthm   currently available KCNN4 blockers might therefore attenuate tissue fibrosis and remodeling in patients with diseases such as idiopathic pulmonary fibrosis and asthma through the inhibition of fibrocyte recruitment immunology autoimmune digestive it may be possible to rapidly test whether KCa3.1 inhibitors are efficacious in patients with inflammatory bowel diseases such as Crohn disease and ulcerative colitis cardiovascular atheroma   CKCNN4 blockers represent a promising therapeutic strategy for atherosclerosis. miscelleaneous urinary chronic kidney disease pharmacological inhibitors of KCNN4 channels may provide a novel and effective therapy to delay progression to kidney failure in patients with ADPKD

ANIMAL & CELL MODELS