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FLASH GENE

Symbol

PTTG1IP

contributors: mct - updated : 23-01-2013

HGNC name	pituitary tumor-transforming 1 interacting protein
HGNC id	13524

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in thyroid cancer tumoral     --over   causes thyroid cell proliferation, macrofollicular lesions, and hyperplasia, as well as repression of the critical therapeutic route for radioiodide uptake

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer endocrine thyroid novel target for improving radioiodine uptake and thus prognosis in thyroid cancer.

ANIMAL & CELL MODELS