| Symbol
| CDH13
| contributors: mct - updated : 15-02-2019
|
| HGNC name
| cadherin 13, H-cadherin (heart)
|
| HGNC id
| 1753
|
| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
|
| deletion
|
|
| |
in lung carcinoma | | tumoral
|
|
| --low
|
| |
hypermethylated or deleted in ovarian, breast, lung and in colorectal cancer and adenoma | | tumoral
|
|
| --low
|
| |
in diffuse large B cell lymphomas (B-DLCLs) by promoter hyper-methylation | | tumoral
|
|
| --low
|
|
by promoter hypermethylation is a common, early event in esophageal adenocarcinogenesis and correlates with clinical risk factors  | | tumoral
|
|
| --low
|
| |
in cutaneous squamous cell carcinoma | |
| Susceptibility
|
to Attention-deficit/hyperactivity disorder, ADHD to type 2 diabetes (T2DM) |
| Variant & Polymorphism
SNP
| association between the SNP-rs12596316 genotype and T2DM |
| 
|
| Candidate gene
| detection of methylation of the gene in blood might have utility in monitoring and detecting tumor recurrence in early-stage non-small cell lung cancer after curative surgical resection |
Marker
Therapy target
|
| | |
|
| mice lacking Cdh13 exhibit reduced cognitive flexibility and loss of preference for contact region concomitant with increased reciprocal social interactions |