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FLASH GENE

Symbol

CDH8

contributors: shn/npt - updated : 10-08-2009

HGNC name	cadherin 8, type 2
HGNC id	1767

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	blockade of the cadherin-8 in cultured rat hippocampal neurons leads to an alterations of dendritic spine morphology
	Chd8–/– mice died early during embryogenesis, manifesting widespread apoptosis, whereas deletion of p53 ameliorated this developmental arrest