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FLASH GENE
Symbol CDH8 contributors: shn/npt - updated : 10-08-2009
HGNC name cadherin 8, type 2
HGNC id 1767
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • blockade of the cadherin-8 in cultured rat hippocampal neurons leads to an alterations of dendritic spine morphology
  • Chd8/ mice died early during embryogenesis, manifesting widespread apoptosis, whereas deletion of p53 ameliorated this developmental arrest