Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PCDH7

contributors: mct - updated : 21-04-2020

HGNC name	protocadherin 7
HGNC id	8659

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   by hypermethylation in Androgen-independent prostate cancer (AIPC) tumoral     --over   in a large number of patients with Castrate resistant prostate cancer (CRPC) tumoral     --over   frequently in Non-small cell lung cancer (NSCLC) where this event is associated with poor clinical outcome

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	can serve as a novel biomarker for diagnostic and prognosis in patients with gastric cancer
	low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC)
Therapy target
	System Type Disorder Pubmed cancer reproductive prostate PCDH7 may be an attractive target in subsets of patients with Castrate resistant prostate cancer (CRPC)

ANIMAL & CELL MODELS