Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ECM1 contributors: mct - updated : 04-04-2016
HGNC name extracellular matrix protein 1
HGNC id 3153
ASSOCIATED DISORDERS
corresponding disease(s) HCMU
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in metastatic epithelial cells (breast, esophageal, gastric and colorectal)
constitutional     --low  
decrease of elastic fibers and extracellular matrix 1 protein was present in the hyalinization zone of lichen sclerosus compared to healthy controls
tumoral     --over  
may contribute to cholangiocarcinoma (CCA) initiation and progression through promoting migration and invasion of CCA cells
constitutional       loss of function
caused impaired T(H)2 responses and reduced allergic airway inflammation
Susceptibility to ulcerative colitis
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS