Symbol
| FGF14
| contributors: mct - updated : 27-08-2015
|
HGNC name
| fibroblast growth factor 14
|
HGNC id
| 3671
|
corresponding disease(s)
|
SCABG
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
|  
| loss of function
|
impairs spontaneous and repetitive firing in Purkinje neurons by altering the expression of SCN8A channels  | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| inactivation of Fgf14 in mice results in markedly reduced Purkinje neuron excitability  |