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FLASH GENE

Symbol

ADRB3

contributors: mct - updated : 06-02-2019

HGNC name	adrenergic, beta-3-, receptor
HGNC id	288

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ADRB3

related resource

Obesity at GeneDis (beta-3-adrenergic receptor)

Susceptibility

for hypertension in the Sardinian population and for obesity in Mexican-American population for non insulin dependent type 2 diabetes for obesity

Variant & Polymorphism SNP	polymorphism W64R
	allele Arg64 increases the risk of non insulin dependent type 2 diabetes
	ADRB3 Arg64 allele had a significantly higher relative body weight and relative body mass index compared with non-carriers

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     is promising, novel targets for anti-cancer therapy

ANIMAL & CELL MODELS