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FLASH GENE

Symbol

IRF1

contributors: mct/npt/pgu - updated : 28-03-2020

HGNC name	interferon regulatory factor 1
HGNC id	6116

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral   deletion     in MDS, AML, differentiated gastric adenocarcinomas (see TSG5D)

Susceptibility

putative susceptibility gene for rheumatoid arthritis and for asthma to Beh et disease with thrombotic event

Variant & Polymorphism other	frequency of the CAAA haplotype was significantly higher in BD patients that had experienced a thrombotic event

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS