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FLASH GENE

Symbol

FOXI1

contributors: - updated : 23-05-2007

HGNC name	forkhead box I1
HGNC id	3815

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional germinal mutation       in Pendred syndrome constitutional germinal mutation       in hearing loss associated with enlarged vestibular aqueduct (DFNB4)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

mice with a targetted disruption of Frhl10 have a gross structural malformation of the cochlea and vestibulum replaced by a single irregular cavity