Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

VCAM1

contributors: mct - updated : 12-07-2017

HGNC name	vascular cell adhesion molecule 1
HGNC id	12663

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   on blood vessels and muscle fibres in inflammatory myopathies as compared to controls constitutional     --over   in Alzheimer disease, and VCAM1 levels significantly reflected the severity of dementia constitutional     --other   expression by cholangiocytes in chronic hepatitis contributes to persistent inflammation

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	appears to be useful in risk stratification of chronic heart failure (CHF) patients and in screening, to identify subjects at risk for heart failure related events
Therapy target
	System Type Disorder Pubmed neurosensorial visual retina antagonism of VCAM1 provides a potential therapy to combat worsening of neovascular diseases by oxidative stress cancer     potential target in cancer treatment cancer reproductive breast targeting VCAM1 is an attractive strategy for therapeutic intervention

ANIMAL & CELL MODELS