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FLASH GENE

Symbol

HOXD11

contributors: mct/npt - updated : 16-03-2009

HGNC name	homeobox D11
HGNC id	5134

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

PSDY2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   by aberrant promoter methylation in ovarian cancers (Cai 2007) constitutional   deletion     of the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities tumoral fusion       to NUP98 in acute myeloid leukemia with t(2;11)(q31;p15)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS