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FLASH GENE
Symbol CEBPB contributors: mct/npt/pgu - updated : 04-01-2015
HGNC name CCAAT/enhancer binding protein (C/EBP), beta
HGNC id 1834
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   amplification    
in many solid tumors including gastric cancers
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
obesity  
may be an attractive therapeutic target for ameliorating obesity-induced inflammatory responses
ANIMAL & CELL MODELS
  • chimeric bone marrow mice transplanted with bone marrow lacking C/EBP(-/-) demonstrated reduced systemic and adipose tissue inflammatory markers, macrophage content, and maintained insulin sensitivity on high fat diet