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FLASH GENE

Symbol

TSR2

contributors: mct - updated : 02-01-2023

HGNC name	TSR2 ribosome maturation factor
HGNC id	25455

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

DBA14

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in laryngeal squamous cell carcinoma (LSCC)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer head and neck   TSR2-induced apoptosis was mediated by inhibiting the NFKB1 signaling pathway, which may provide an effective target in gene therapy for LSCC

ANIMAL & CELL MODELS