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FLASH GENE
Symbol MUL1 contributors: SGE/npt - updated : 13-06-2019
HGNC name mitochondrial E3 ubiquitin ligase 1
HGNC id 25762
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral        
in head and neck cancer (HNC)
Susceptibility
  • to Parkinson disease (PD)
  • Variant & Polymorphism SNP
  • rs529974 in MUL1 gene was significantly associated with the risk of PD
  • Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerhead and neck 
    regulation of FOXO3-MUL1-AKT1 axis can be a novel strategy for the treatment of head and neck cancer (HNC) with cisplatin (CDDP)
    cancerhead and neck 
    regulation of the MUL1-HSPA5 axis can be a novel strategy for the treatment of HNC
    ANIMAL & CELL MODELS