Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol AFF1 contributors: mct - updated : 17-06-2020
HGNC name AF4/FMR2 family, member 1
HGNC id 7135
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral fusion      
fusion partner with MLL in a patient affected by acute lymphoblastic leukemia
Susceptibility to systemic lupus eyrthematosus (SLE)
Variant & Polymorphism other
  • association of a variant in AFF1 at 4q21 with SLE susceptibility systemic lupus eyrthematosus
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
    point mutation in Aff1/Af4 causes a dominant form of cerebellar ataxia in mouse