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FLASH GENE
Symbol CEBPG contributors: mct/npt - updated : 05-01-2022
HGNC name CCAAT/enhancer binding protein (C/EBP), gamma
HGNC id 1837
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral       gain of function
in a subset of acute myeloid leukemia (AML) samples characterized by CEBPA hypermethylation/silencing
Susceptibility to bronchogenic carcinoma
Variant & Polymorphism other several polymorphisms contributing to risk for bronchogenic carcinoma (Crawford 2007)
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Cebpg(-/-) mouse embryonic fibroblasts (MEFs) proliferated poorly, entered senescence prematurely, and expressed a proinflammatory gene signature