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FLASH GENE

Symbol

SLAMF6

contributors: mct - updated : 16-02-2016

HGNC name	SLAM family member 6
HGNC id	21392

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   LY9 and SLAMF6 expression is increased on the surface of SLE T cells compared with normal cells

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

deletion of Slamf6 in CD4(+) T cells reversed the Sh2D1a(-/-) phenotype, eliminating the SH2D1A requirement for germinal centers